Ocular characteristics and complications in patients with osteogenesis imperfecta: a systematic review
نویسندگان
چکیده
منابع مشابه
The craniofacial characteristics of osteogenesis imperfecta patients.
The aim of this study was to identify the craniofacial characteristics of 16 osteogenesis imperfecta (OI) patients, 10 males and 6 females, aged 7-15 years. The control group comprised 863 Chinese children from 6 to 18 years of age. Eleven cephalometric reference points and 25 variables were measured on the lateral cephalometric radiographs. Cochrane's method of unequal variance t-test was used...
متن کاملOsteogenesis Imperfecta: A Review with Clinical Examples.
Osteogenesis imperfecta (OI) is characterized by susceptibility to bone fractures, with a severity ranging from subtle increase in fracture frequency to prenatal fractures. The first scientific description of OI dates from 1788. Since then, important milestones in OI research and treatment have, among others, been the classification of OI into 4 types (the 'Sillence classification'), the discov...
متن کاملA Systematic Overview of Osteogenesis Imperfecta
Osteogenesis imperfecta (OI) is a heterogeneous rare connective tissue disorder commonly caused by mutations in the collagen type 1 gene. It is a worldwide extensive disorder regardless of age, gender or ethnic group for a children and adults. Typical clinical features are brittle bone, high frequency of fractures and bone deformities. The other observed signs are blue sclera, dentinogenesis im...
متن کاملThe Spine in Patients With Osteogenesis Imperfecta.
Osteogenesis imperfecta is a genetic disorder of type I collagen. Although multiple genotypes and phenotypes are associated with osteogenesis imperfecta, approximately 90% of the mutations are in the COL1A1 and COL1A2 genes. Osteogenesis imperfecta is characterized by bone fragility. Patients typically have multiple fractures or limb deformity; however, the spine can also be affected. Spinal ma...
متن کاملPersonalized medicine in patients with Osteogenesis imperfecta
Results With this change of therapy we were able to reduce bone resorption to the normal range [2]. After two years of treatment both patients show an increase of bone mineral density of the lumbar spine with a z-score from – 2.4 to -2.0 and -4.3 to 2.5 respectively and an increase of projected vertebral area L2 – L4 [mm2] from 1670 to 2152 and from 1424 to 1528. No severe side effects were see...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Ophthalmologica
سال: 2021
ISSN: 1755-375X,1755-3768
DOI: 10.1111/aos.14882